کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3950208 1600412 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Selected metabolic parameters and the risk for uterine fibroids
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Selected metabolic parameters and the risk for uterine fibroids
چکیده انگلیسی

ObjectiveTo analyze the possible association between insulin resistance and dyslipidemia with uterine fibroids, using objective metabolic measurements.MethodA cross-sectional study of 56 women with uterine fibroids (case group) and 20 women without fibroids (control group). Levels of fasting glucose, insulin, C-peptide, sex hormone-binding globulin, and the lipid panel were measured. The short insulin tolerance test was performed. Body mass index, atherogenic index, and the indicator of insulin resistance (Kitt) were also calculated.ResultsWomen with fibroids had significantly higher levels of serum HDL-cholesterol compared with control patients (1.8 ± 0.3 vs 1.6 ± 0.5; P < 0.05). Women with fibroids aged 30–45 years had significantly lower LDL-cholesterol levels than comparative control patients (2.9 ± 0.7 vs 3.4 ± 0.9; P < 0.05). A positive correlation between volume of the largest fibroid and serum HDL-cholesterol level was found in women aged 30–45 years. There were no differences in indicators of insulin resistance between the groups.ConclusionInsulin resistance was not shown to be a risk factor for fibroids. There is a negative association between some parameters of metabolic syndrome and fibroid volume.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Gynecology & Obstetrics - Volume 102, Issue 1, July 2008, Pages 50–54
نویسندگان
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