Suzuki–Miyaura cross-coupling of aryl iodides and phenylboronic acid over palladium-free CeO2 catalysts

• The Suzuki–Miyaura reaction is carried out over a noble metal-free catalyst.
• Ceria is active for the cross coupling of p-iodotoluene and phenylboronic acid.
• Ceria activity and selectivity for the SM reaction depends on pre-treatment.
• Acid sites on ceria surface are active for Suzuki–Miyaura reaction.

The Suzuki–Miyaura cross-coupling reaction between p-iodotoluene and phenylboronic acid is carried out over a series of ceria catalysts, at 150 °C, under N2 atmosphere, employing DMF as the solvent. The ceria catalysts present different BET area (determined from N2 isotherms at 77 K), different Ce4+/Ce3+ ratio (as measured by XPS), and different concentration and strength of acid sites (as measured by potentiometric titration with n-butylamine). The activity of the different samples depends on the concentration and strength of acid sites, although the participation of Ce3+ centers should not be neglected. Ceria catalysts are less active and less selective than a Pd/SiO2 sample. Although the catalytic performance of ceria catalysts is lower than the one corresponding to Pd/SiO2, the fact that a transition metal-free catalyst is active for SM reaction is highlighted.

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