کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3964392 | 1600714 | 2012 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Maternal serum interleukin-33 and soluble ST2 across early pregnancy, and their association with miscarriage
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Maternal serum interleukin-33 and soluble ST2 across early pregnancy, and their association with miscarriage Maternal serum interleukin-33 and soluble ST2 across early pregnancy, and their association with miscarriage](/preview/png/3964392.png)
چکیده انگلیسی
A shift from type 1 to type 2 immune bias is essential for successful implantation and pregnancy. ST2 is a receptor present on type 2 immune cells and IL-33 was recently discovered to be its ligand. We measured serum levels of soluble ST2 (sST2) and IL-33 across the mid-first trimester and examined whether levels were dysregulated among women with a viable fetus but destined to miscarry. While there was no significant change in sST2 or IL-3 across the first trimester, we found that women with live pregnancies destined to fail had dysregulated levels of serum IL-33, and potentially sST2 at six weeks' gestation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Reproductive Immunology - Volume 95, Issues 1â2, September 2012, Pages 46-49
Journal: Journal of Reproductive Immunology - Volume 95, Issues 1â2, September 2012, Pages 46-49
نویسندگان
Tu'uhevaha J. Kaitu'u-Lino, Laura Tuohey, Stephen Tong,