کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3966054 1256134 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Letrozole versus artificial hormonal endometrial preparation for vitrified–warmed embryos transfer cycles
ترجمه فارسی عنوان
لتروزول در مقابل آماده سازی اندومتر هورمون های مصنوعی برای تجمع چربی های جنینی گرم شده
کلمات کلیدی
لتروزول، ظاهر شیشه ای گرم شدن آندومتر
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی

Objective: To evaluate the efficacy of letrozole in the endometrial preparation of vitrified–warmed embryo transfer cycles and to compare it to the hormonal preparation with estradiol valerate and progesterone study. Design: Retrospective observational study. Methods: We analyzed 197 cycles of endometrial preparation for vitrified–warmed embryo transfer from January 2013 to August 2014. A final 94 cycles of letrozole were compared to 96 cycles of hormonal preparation. Results: Pregnancy rate was non significantly higher in the letrozole group (53.2%) than in the hormonaly prepared group (40.6%) while the ongoing pregnancy rate was significantly higher in the letrozole group 47.9% v 32.3% (P value 0.02). The abortion rate was non significantly lower in the letrozole group 5.3% v 8.3%. The mean endometrial thickness in the hormonaly prepared group was significantly higher than the letrozole 9.9 mm ± 1.7 and 9.1 mm ± 1.6 respectively. Conclusion: Endometrial preparation for vitrified-warmed embryo transfer using the aromatase inhibitor letrozole has a significantly higher ongoing pregnancy rate than that of the hormonal preparation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Middle East Fertility Society Journal - Volume 21, Issue 2, June 2016, Pages 96–100
نویسندگان
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