کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3966122 1256138 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Validation of the Risk of Malignancy Index in primary evaluation of ovarian masses
ترجمه فارسی عنوان
اعتبار سنجی شاخص خطر ابتلا به بدخیمی در ارزیابی اولیه توده تخمدان
کلمات کلیدی
خطر ابتلا به بدخیمی ارزیابی اولیه، توده های تخمدان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی

Objective: To determine the effectiveness of RMI in identifying cases of potential ovarian malignancy, and to compare the performance of RMI-4 and RMI-3 in predicting ovarian malignancy. Design: Retrospective descriptive study. Materials and methods: Women who underwent surgery for adenxal mass between January 2010 and December 2012 were included in this retrospective study. Age, menopausal status, ultrasound findings and CA-125 serum levels and final histopathology report of the excised tumor were extracted from the records. RMI-3 and RMI-4 were calculated and their performances in prediction of borderline and malignant ovarian cancer were compared. Results: 172 patients were included; 131 (76.2%) benign, 15 (8.7%) borderline, and 26 (15.1%) malignant tumors. In patients with malignant ovarian masses, RMI-3 gave sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) and diagnostic accuracy of 80.7%, 93.1%, 70%, 96% and 91% respectively. For RMI-4 these figures were 76.9%, 93.8%, 71.4%, 95.3%, and 91% respectively. In patients with borderline ovarian masses, RMI-3 gave sensitivity, specificity, PPV, NPV and diagnostic accuracy of 60%, 93.1%, 50%, 95.3% and 83.7% respectively. For RMI-4 these figures were 52.9%, 93.1%, 50%, 93.8%, and 88.5% respectively. Both RMI-3 and RMI-4 are more accurate in predicting malignant rather than borderline adenxal masses. Main outcome measures: Accuracy indices of RMI-3 and RMI-4. Conclusion: RMI is a simple, reliable and applicable method in the primary evaluation of patients with ovarian masses. The performance of RMI-3 and RMI-4 is comparable.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Middle East Fertility Society Journal - Volume 19, Issue 4, December 2014, Pages 324–328
نویسندگان
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