کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3966280 1256149 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Leukocytospermia: Overview of diagnosis, implications, and management of a controversial finding
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Leukocytospermia: Overview of diagnosis, implications, and management of a controversial finding
چکیده انگلیسی

BackgroundThe progress in assisted reproductive techniques over the last 30 years has raised interest in studying what in 1992 the World Health Organization (WHO) defined as abnormal: the presence of >1 × 106 leukocytes/mL in a semen sample. Leukocytospermia is found in both fertile and infertile men with and without evidence of infections of the genital tract. However, despite extensive research done in this subject, the clinical implications of this condition remain unclear.ResultsThe accuracy that the cut-off value that defines leukocytospermia has in predicting clinical significance remains unclear. Furthermore, there are conflicting data supporting a physiologic and pathologic role of leukocytes in a semen sample through the generation of reactive oxygen species. Although some authors describe no effects on fertilization and pregnancy outcomes after in vitro fertilization with or without intra-cytoplasmic sperm injection, others suggest the exact opposite. Finally, research on treatment of leukocytospermia with vitamin E, COX-2 inhibitors and antibiotics has also shown contradicting data.ConclusionsThus, it seems reasonable to agree that there is no agreement on the diagnosis, implications, and management of leukocytospermia in patients without evidence of genital tract infection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Middle East Fertility Society Journal - Volume 18, Issue 3, September 2013, Pages 129–134
نویسندگان
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