کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3966285 1256149 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Maternal serum copeptin as a marker for fetal growth restriction
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Maternal serum copeptin as a marker for fetal growth restriction
چکیده انگلیسی

ObjectivesCopeptin is a hormone of endogenous stress. The aim was to evaluate whether the measurement of maternal serum copeptin is useful for differentiation between fetal growth retardation and constitutionally small fetuses among small for gestational age fetuses.Study Designprospective case control clinical study.Patients and MethodsMaternal serum copeptin levels were measured by ELISA technique in 53 pregnant females subdivided into a control group (group 1) of 20 women with normal gestation & a group of 33 pregnant women with small for gestational age fetuses. The small for gestational age fetuses were subclassified into constitutionally small fetuses (17 cases) with normal umbilical artery Doppler studies (group 2), and fetal growth restriction with abnormal umbilical artery Doppler studies (16 idiopathic cases) as group 3.ResultsThe fetal growth restricted group had a significantly higher maternal serum copeptin levels as compared with the control group (P < 0.01). The maternal serum copeptin levels in fetal growth restriction were significantly higher than in constitutionally small fetus (P < 0.05).ConclusionMaternal serum copeptin level can differentiate between the normal sized and small for gestational age fetuses. Also, it can differentiate between constitutionally small and growth restricted fetuses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Middle East Fertility Society Journal - Volume 18, Issue 3, September 2013, Pages 159–164
نویسندگان
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