Value of endometrial dyeing in diagnosis of endometritis in the absence of macroscopic abnormalities during hysteroscopy

ObjectiveTo evaluate endometrial dyeing with methylene blue dye during hysteroscopy in diagnosis of endometritis.DesignProspective cohort study.Materials and methodsThe study included 57 patients with absent macroscopic pathology on transvaginal sonography and hysteroscopy. Endometrial features were described after methylene blue dye injection at hysteroscopy. Patients were classified into two groups. Group I (n=41) with diffuse light staining and Group II (n=16) with focal dark blue staining. Endometrial biopsy was then taken for histopathological examination.ResultsThere was a significant difference in diagnosis of chronic endometritis between both groups. Group I 3/41 (7.31%) and Group II 7/16 (43.57%) and P value was <0.05 in comparing both groups. Group II showed sensitivity (70%), specificity (80.8%), positive predictive value (43.7%) and negative predictive value (92.6%).ConclusionEndometrial dyeing with methylene blue dye is a valuable tool at hysteroscopy for diagnosis of chronic endometritis and should be applied to such cases.