Endometrial cancer

Endometrial cancer is the most common gynaecological malignancy in the United Kingdom, and an understanding of its presentation and management options is required for all gynaecologists. The surgical management of endometrial cancer has expanded to include laparoscopic surgery, and debate is ongoing regarding the utility of pelvic and para-aortic lymphadenectomy. Our understanding of the biology of endometrial cancer may help determine which women may benefit most from chemo- or hormonal therapy, which may be promising in an adjuvant setting. Pelvic radiation is associated with better local control. Combination therapy with radiation and chemotherapy is under evaluation.