کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3975086 1600972 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clinical significance of serum follistatin levels in the diagnosis of ovarian endometrioma and benign ovarian cysts
ترجمه فارسی عنوان
اهمیت بالینی سطح فولستاتین سرم در تشخیص آندومتریوم تخمدان و کیست خوش خیم تخمدان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی

ObjectiveTo determine the clinical significance of serum follistatin levels in women with an ovarian endometrioma.Materials and methodsThis is a prospective study of 89 women, 56 with an ovarian endometrioma (endometrioma group) and 33 with a benign ovarian cyst (control group) who underwent laparoscopic excision. Age, parity, body mass index, serum CA-125, serum CA 19-9, and serum follistatin levels were determined for all participants and evaluated as potential prognostic factors prior to laparoscopic cystectomy.ResultsThere were no significant differences in demographic factors between the endometrioma group and the control group. However, serum follistatin levels were significantly higher in the endometrioma group (9350 ± 895 pg/mL vs. control group 725 ± 72 pg/mL, p < 0.05). The optimal diagnostic cut-off values (sensitivity and specificity) of CA-125, CA 19-9, and follistatin for ovarian endometrioma were 23.2 IU/mL (82.14% and 72.73%), 30.14 IU/mL (45.28% and 87.50%), and 2350 pg/mL (53.7% and 60.61%), respectively.ConclusionDespite the increased serum follistatin levels in patients with ovarian endometrioma, CA-125 was determined to be a more sensitive and specific marker than follistatin for the diagnosis of ovarian endometrioma and endometriosis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Taiwanese Journal of Obstetrics and Gynecology - Volume 54, Issue 3, June 2015, Pages 236–239
نویسندگان
, , , , , ,