کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4011972 1261172 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The genetics of primary open-angle glaucoma: A review
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی و میکروب شناسی (عمومی)
پیش نمایش صفحه اول مقاله
The genetics of primary open-angle glaucoma: A review
چکیده انگلیسی

Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder and affects more than 2 million individuals in the United States. It has become increasingly clear that a host of genetic as well as environmental factors are likely to contribute to the phenotype. A number of chromosomal and genetic associations have been reported for POAG. This review examines what is currently known about the underlying genetic structure, what remains to be learned, and how this may affect our medical management of this major blinding disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Eye Research - Volume 88, Issue 4, 30 April 2009, Pages 837–844
نویسندگان
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