کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4035068 1263504 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Retinal degeneration in children: Dark adapted visual threshold and arteriolar diameter
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
پیش نمایش صفحه اول مقاله
Retinal degeneration in children: Dark adapted visual threshold and arteriolar diameter
چکیده انگلیسی

To assess the condition of the retina in children with retinal degeneration due to Bardet-Biedl syndrome (BBS, n = 41), Leber congenital amaurosis (LCA, n = 31), or Usher syndrome (USH, n = 13), the dark adapted visual threshold (DAT) and arteriolar diameters were measured. Compared to controls, the initial DATs of nearly all (83/85) were significantly elevated, and in 26/62 with serial DATs, significant progressive elevation occurred. Arteriolar diameters were significantly attenuated and narrowed with age in BBS and USH, but not LCA. Higher DATs were associated with narrower arterioles. Such non-invasive procedures can document the natural history of these retinal diseases and have the potential to assess response to future treatment.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vision Research - Volume 48, Issue 3, February 2008, Pages 325–331
نویسندگان
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