کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4040510 | 1603304 | 2014 | 13 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The motor function measure to study limitation of activity in children and adults with Charcot-Marie-Tooth disease The motor function measure to study limitation of activity in children and adults with Charcot-Marie-Tooth disease](/preview/png/4040510.png)
ObjectiveTo study the applicability and responsiveness of the motor function measure (total score and sub-scores D1, D2 and D3) in patients with Charcot-Marie-Tooth disease.Patients and methodsTwo hundred and thirty-three patients aged 4–86 years were included in the descriptive study. Scores and sub-scores were analyzed by age and by disease subtypes. Sensitivity to change (responsiveness) was estimated in patients having had at least two evaluations with at least six months between the first and the second.ResultsMotor function measure scores decrease with age, especially sub-scores D1 and D3. There were no significant differences between the scores according to type of Charcot-Marie-Tooth disease. The scores were significantly higher for ambulatory than for non-ambulatory patients. Significant responsiveness was demonstrated only in type 2 Charcot-Marie-Tooth disease.Discussion/conclusionsOur results suggest that, especially for D1 and D3 sub-scores, the motor function measure is a reliable and valid outcome measure that can be usefully applied in longitudinal follow-up. Studies of longer duration could demonstrate its responsiveness in other Charcot-Marie-Tooth disease subtypes.
RésuméObjectifÉtudier l’applicabilité et la sensibilité au changement du score total et des trois sous-scores, D1, D2 et D3 de la mesure de fonction motrice chez des patients atteints de maladie de Charcot-Marie-Tooth.Patients et méthodesÉtude descriptive sur 233 patients âgés de 4 à 86 ans. Les scores ont été analysés en fonction de l’âge et du type de la maladie. Les sensibilités au changement ont été étudiées chez les patients ayant eu au moins deux évaluations espacées d’au moins six mois.RésultatsLes scores de la Mesure de Fonction Motrice diminuent avec l’âge, surtout les sous-scores D1 et D3. Il n’existe pas de différence significative en fonction du type de la maladie. Les scores des patients non ambulants sont significativement plus faibles que ceux des patients ambulants. La sensibilité au changement est significative chez les Charcot-Marie-Tooth type 2.ConclusionLa mesure de fonction motrice est une échelle applicable, surtout D1 et D3, au suivi des patients atteints de la maladie de Charcot-Marie-Tooth de façon longitudinale. Sa sensibilité au changement nécessite d’être confirmée en utilisant des durées d’étude plus longues compte tenu de l’évolutivité de la maladie.
Journal: Annals of Physical and Rehabilitation Medicine - Volume 57, Issues 9–10, December 2014, Pages 587–599