کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4050886 1264963 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Knee biomechanics during walking gait following matrix-induced autologous chondrocyte implantation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
پیش نمایش صفحه اول مقاله
Knee biomechanics during walking gait following matrix-induced autologous chondrocyte implantation
چکیده انگلیسی

BackgroundMatrix-induced autologous chondrocyte implantation is a technique for repairing articular cartilage defects in the knee. Despite reported improvements in pain, little is known about the recovery of knee biomechanics during walking gait.MethodsA randomized controlled study design was used to investigate knee biomechanics during gait in 61 patients following matrix-induced autologous chondrocyte implantation, in conjunction with either ‘accelerated’ or ‘traditional’ approaches to post-operative weight-bearing rehabilitation. Gait analysis was performed at 3, 6 and 12 months post-surgery in both patient groups, and two matched, unaffected control groups for comparison.FindingsThe spatiotemporal and ground reaction force parameters were similar between patient groups and their respective control groups at all time points. When compared with controls, both patient groups demonstrated significantly reduced knee extension moments up until, and including, 12 months. The traditional group demonstrated a significantly reduced knee adduction moment at 3, 6 and 12 months, and a significantly reduced knee flexion moment at 3 months. There were no differences in these knee moments between the accelerated patient group and controls.InterpretationOverall, a higher level of gait dysfunction was observed in patients who underwent traditional rehabilitation. Future research is needed to investigate the recovery of normal gait following matrix-induced autologous chondrocyte implantation, and its effect on repair tissue development.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Biomechanics - Volume 25, Issue 10, December 2010, Pages 1011–1017
نویسندگان
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