کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4060776 | 1604025 | 2012 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Heparin-Induced Thrombocytopenia After Total Knee Arthroplasty, With Subsequent Adrenal Hemorrhage
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ارتوپدی، پزشکی ورزشی و توانبخشی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Heparin-Induced Thrombocytopenia After Total Knee Arthroplasty, With Subsequent Adrenal Hemorrhage Heparin-Induced Thrombocytopenia After Total Knee Arthroplasty, With Subsequent Adrenal Hemorrhage](/preview/png/4060776.png)
چکیده انگلیسی
Heparin-induced thrombocytopenia (HIT) is a life-threatening immune-mediated adverse effect of chemoprophylaxis for venous thromboembolic events. We present the case of a 44-year-old man who developed bilateral adrenal hemorrhage (BAH) as a sequela of HIT after bilateral total knee arthroplasty. In our review of clinical management of HIT-induced BAH, we discuss the 21 published cases of this phenomenon, 14 of which occurred after orthopedic surgery. Given the potentially fatal consequences and the importance of early intervention, physicians should be on the alert for recognizing HIT-induced BAH in patients experiencing shock unresponsive to fluid resuscitation. In addition, chemoprophylaxis with alternative agents such as a synthetic pentasaccharide factor Xa inhibitor and oral direct thrombin inhibitors that are associated with lower risks of HIT in orthopedic patients merits exploration.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Arthroplasty - Volume 27, Issue 7, August 2012, Pages 1413.e15-1413.e18
Journal: The Journal of Arthroplasty - Volume 27, Issue 7, August 2012, Pages 1413.e15-1413.e18
نویسندگان
Vinca W. BSc, Freddy MD, James I. MD, Ludwig H. MD,