Patient-Related Predictors of Treatment Failure After Primary Total Knee Arthroplasty for Osteoarthritis

The aim was to identify patient-related predictors of treatment failure after primary total knee arthroplasty for osteoarthritis. Treatment failure included surgical revision or clinical failure, which was defined by less than 70 in any score of the Knee Society. Prospective follow-up was performed in 412 consecutive patients with a minimum of 5 years. Multivariate logistic regression analysis revealed that higher Charlson index, worse preoperative Knee Society function, and Western Ontario McMaster University pain component were significantly associated with treatment failure. This study identified clinically important patient-related predictors of treatment failure after TKA, which may be useful preoperatively in identifying patients with risk of failure.