کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4061097 1604012 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preclinical Evaluation of a Novel Implant for Treatment of a Full-Thickness Distal Femoral Focal Cartilage Defect
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
پیش نمایش صفحه اول مقاله
Preclinical Evaluation of a Novel Implant for Treatment of a Full-Thickness Distal Femoral Focal Cartilage Defect
چکیده انگلیسی

A novel, nonresorbable, monolithic composite structure ceramic, developed using a partially stabilized zirconia ceramic common to implantable devices, was used in a cementless weight-bearing articular implant to test the feasibility of replacing a region of degenerated or damaged articular cartilage in the knee as part of a preclinical study using male mongrel dogs lasting up to 24 weeks. Gross/histological cartilage observations showed no differences among control, 12-week and 24-week groups, while pull-out tests showed an increase in maximum pull-out load over time relative to controls. Hence, the use of a novel ceramic implant as a replacement for a focal cartilage defect leads to effective implant fixation within 12 weeks and does not cause significant degradation in opposing articular cartilage in the time frame evaluated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Arthroplasty - Volume 28, Issue 8, September 2013, Pages 1421–1429
نویسندگان
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