کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4061813 1604021 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tranexamic Acid for Reduction of Blood Loss During Total Hip Arthroplasty
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
پیش نمایش صفحه اول مقاله
Tranexamic Acid for Reduction of Blood Loss During Total Hip Arthroplasty
چکیده انگلیسی

In this study, we evaluated the hemostatic effects of tranexamic acid (TNA), an antifibrinolytic drug, by examining the timing of its administration during total hip arthroplasty. One hundred seven patients being treated for osteoarthritis of the hip joint were randomly divided into 5 groups based on the timing of TNA administration. The intraoperative blood loss, postoperative blood loss, and hemoglobin of these patients who received TNA at different times during the procedure were monitored. We found that the intraoperative blood loss in the preoperative TNA administration groups was significantly lower than both control and postoperative TNA administration groups. Furthermore, 1 g TNA 10 minutes before surgery and 6 hours after the first administration was most effective for the reduction of blood loss during total hip arthroplasty.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Arthroplasty - Volume 27, Issue 10, December 2012, Pages 1838–1843
نویسندگان
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