کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4062065 | 1604031 | 2012 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A Prospective Comparison of Warfarin to Aspirin for Thromboprophylaxis in Total Hip and Total Knee Arthroplasty
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کلمات کلیدی
Arthroplasty - آرتروپلاستیPulmonary embolism - آمبولی ریهAmerican Academy of Orthopaedic Surgeons - آکادمی آمریکایی جراحان ارتوپدیVenous thromboembolism - ترومبوآمبولی وریدیtotal knee - زانو کاملAmerican College of Chest Physicians - کالج آمریکایی پزشکان قفسه سینهtotal hip - کل رانGuidelines - گایدلاین یا دستورالعمل
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ارتوپدی، پزشکی ورزشی و توانبخشی
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چکیده انگلیسی
Current orthopedic practice requires consideration of contradictory recommendations regarding pulmonary embolism (PE) prevention among patients undergoing total hip arthroplasty (THA) and knee joint arthroplasty (TKA). A total of 696 consecutive patients underwent elective THA or TKA. Two hundred eighty-one patients received PE risk stratification per American Academy of Orthopaedic Surgeons guidelines. Of these patients, 152 standard-risk patients received aspirin, and 129 elevated-risk patients received warfarin. The comparator group of 415 patients received American College of Chest Physicians-recommended warfarin without PE risk stratification. Primary study outcomes were symptomatic PE, deep venous thrombosis, major bleeding, and death. The rate of symptomatic PE and venous thromboembolism among standard-risk group patients receiving aspirin was greater than the comparator group (4.6% vs 0.7% and 7.9% vs 1.2%, respectively). Most events (16/18) occurred among patients undergoing TKA. Patients with total joint arthroplasty at standard risk for PE receiving aspirin had a higher rate of symptomatic PE and venous thromboembolism than did patients receiving anticoagulation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Arthroplasty - Volume 27, Issue 1, January 2012, Pages 1-9.e2
Journal: The Journal of Arthroplasty - Volume 27, Issue 1, January 2012, Pages 1-9.e2
نویسندگان
Intermountain Joint Replacement Center Writing Committee Intermountain Joint Replacement Center Writing Committee,