Electron microscopic study on bone formation and bioresorption after implantation of β-tricalcium phosphate in rabbit models

These findings suggest that cell-mediated disintegration by osteoclasts played a role in the bioresorption of β-TCP at an early stage after implantation. In addition, the micropores of β-TCP ceramic may provide an environment for collagen formation, leading to the deposition of apatite crystals. Therefore, the micropores facilitate bone ingrowth as well as ceramic resorption.