کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4079113 | 1267348 | 2010 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mediators Leading to Fibrosis-How to Measure and Control Them in Tissue Engineering
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ارتوپدی، پزشکی ورزشی و توانبخشی
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چکیده انگلیسی
Fibrosis is the result of an excessive amount of fibrous connective tissue deposited into the extracellular matrix space of damaged tissues from injury or disease. Collagens, particularly types I and III are the main constituents of the fibrotic scar tissue as well as a mixture of fibrotic cells. Fibrotic tissue will develop chronic healing problems severely resulting in tissue/organ dysfunction. More attention needs to be given to the fibrotic differentiation and related effects in bioengineered tissues. The current review provides an update on the mechanism behind fibrosis formation as well as technical measurements and preventions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Operative Techniques in Orthopaedics - Volume 20, Issue 2, June 2010, Pages 110-118
Journal: Operative Techniques in Orthopaedics - Volume 20, Issue 2, June 2010, Pages 110-118
نویسندگان
Xiaodong PhD, Ian H. BS, Thomas J. PhD, Yong MD, PhD,