A case of intradural osteosarcoma of the spine

Background contextIntradural-extramedullary spinal tumors and extradural osteosarcomas are both rare entities. Only one case of primary intradural-extramedullary osteosarcoma of the spine has been previously reported. This is the second reported case.PurposeTo describe a case of primary intradural-extramedullary osteosarcoma of the spine associated with rapid clinical deterioration.Study designCase report of a 70-year-old woman who presented with a constellation of neurologic symptoms.MethodsReview of patient files, radiographic studies, surgical images, histopathology, and relevant literature.ResultsThe patient underwent tumor debulking but exhibited rapid, postsurgical, functional deterioration and died within 6 weeks. This case and the only previous case of its kind both occurred in individuals with a remote history of iophendylate (Myodil) myelogram.ConclusionsPrimary intradural-extramedullary extraosseous osteosarcoma of the spine is an exceedingly rare entity with no established management approach. Iophendylate myelography may be implicated in the etiology of this tumor type.