کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4107102 1605404 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ricinus communis biocompatibility histological study in the nose of Cebus apella monkeys
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های گوش و جراحی پلاستیک صورت
پیش نمایش صفحه اول مقاله
Ricinus communis biocompatibility histological study in the nose of Cebus apella monkeys
چکیده انگلیسی

SummaryBone tissue lesions can be caused by congenital and acquired factors, and result in nasal deformities with cosmetic and functional repercussion. Surgical treatment in these cases frequently requires complex reconstructions and the use of biomaterials. The polyurethane derived from castor beans (Ricinus communis) has a favorable formulation in terms of ease of processing, flexibility, no emission of toxic vapors and low cost. Nonetheless, despite favorable results, studies about the use of castor beam polymer (Ricinus communis) assessing tissue reaction on the nasal dorsum are still missing in the literature.Aimthe goal of the present investigation is to histologically assess the Ricinus communis polymer implant biocompatibility with the nasal dorsum.Study designexperimental.Materials and Methodswe used four Cebus appela monkeys, in which we created a nasal dorsal defect in all the animals and there we placed the aforementioned implant. The animals were sacrificed 270 days after surgery and the samples were submitted to histological study.Resultsin the histology analysis we did not observe the presence of foreign body granulomas or phagocytic cells. We also observed a progressive bone formation and maturation.Conclusionmacroscopic and microscopic results showed that the castor oil polymer implant was biocompatible.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brazilian Journal of Otorhinolaryngology - Volume 75, Issue 3, May–June 2009, Pages 350–355
نویسندگان
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