Ectopic pyriform sinus parathyroid adenoma

SummaryObjectiveTo describe the diagnosis and treatment of ectopic pyriform sinus parathyroid adenoma.Material and methodsA 44-year-old woman presented with persistent primary hyperparathyroidism after previous failed cervical exploratory surgery.ResultsDiagnosis of ectopic pyriform sinus parathyroid adenoma was suggested by computed tomography and technetium-99 m sestamibi scintigraphy (99mTc-MIBI SPECT/CT). A submucosal tumor was identified under laryngoscopy and resected by endoscopic CO2 laser. Histopathology confirmed the diagnosis of parathyroid adenoma.ConclusionsEctopic pyriform sinus locations are rare in parathyroid adenoma. 99mTc-MIBI SPECT/CT facilitates diagnosis, especially in case of previous failed neck exploration. Endoscopic CO2 laser resection is the treatment of choice.