کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4114701 1606107 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The face does predict the brain—Midline facial and forebrain defects uncovered during the investigation of nasal obstruction and rhinorrhea: Case report and a review of holoprosencephaly and its classifications
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های گوش و جراحی پلاستیک صورت
پیش نمایش صفحه اول مقاله
The face does predict the brain—Midline facial and forebrain defects uncovered during the investigation of nasal obstruction and rhinorrhea: Case report and a review of holoprosencephaly and its classifications
چکیده انگلیسی

SummaryWhen the embryonic forebrain (the prosencephalon) fails to sufficiently divide into the two cerebral hemispheres, holoprosencephaly (HPE) results. This disorder can result in various skull and facial defects with brain abnormalities of varying severity. These brain defects ultimately dictate the prognosis. This varies from death in utero, to normal or near normal brain development. In these less severe cases, otherwise normally developing babies are born with rarely seen midfacial cleft deformities, giving away a structural brain deformity. We report a case of an otherwise developmentally normal seven-year-old boy who was being assessed for nasal obstruction and rhinorrhea. Investigation directed by a high index of suspicion uncovered an occult case of holoprosencephaly.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pediatric Otorhinolaryngology - Volume 70, Issue 5, May 2006, Pages 935–940
نویسندگان
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