کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4115251 | 1606095 | 2007 | 10 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement](/preview/png/4115251.png)
SummaryObjectiveTo evaluate ciprofloxacin 0.3%/dexamethasone 0.1% (CIPRODEX®, Alcon, Ft. Worth, TX) for the prevention of early post-operative otorrhea following TT placement.MethodsThis was a single-center, randomized, evaluator-blinded, parallel-group study. Two hundred children undergoing bilateral TT placement were categorized as having unilateral (“wet/dry”), bilateral (“wet/wet”), or no (“dry/dry”) effusion at the time of surgery. All patients received Ciprodex or no treatment for 5 days post-operatively and returned at 2 weeks.ResultsPhysician-observed otorrhea was reported in 5 (4.95%) patients receiving Ciprodex and 39 (39.39%) patients receiving no treatment (p < 0.0001). Treatment decreased otorrhea in all groups, while the greatest benefit was observed in patients with bilateral effusion (93% reduction). Ciprodex treatment also decreased the rate of clinically diagnosed otitis media (OM) and effusion following TT placement (p ≤ 0.0006).ConclusionCiprodex reduced early post-operative otorrhea, clinically diagnosed OM and effusion following TT insertion. The greatest reduction in otorrhea was observed in patients with bilateral effusion at the time of surgery.
Journal: International Journal of Pediatric Otorhinolaryngology - Volume 71, Issue 5, May 2007, Pages 747–756