کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4132924 1271399 2015 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prognostic factors in malignant pleural mesothelioma
ترجمه فارسی عنوان
عوامل پیش آگهی در مزوتلیوما پالور مزمن
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی آسیب‌شناسی و فناوری پزشکی
چکیده انگلیسی

SummaryMalignant pleural mesothelioma (MPM) is a clinically aggressive tumor originating from mesothelial cells, which line the serosal cavities. Recent years have seen extensive research aimed at identifying new therapeutic targets, predictive markers and prognostic factors in this disease. These include both serum and tissue markers, and are related to multiple cellular pathways which affect cell survival, proliferation, apoptosis, angiogenesis, interaction with the immune response and DNA repair. Several of these molecules may become relevant for pathologists as part of the effort to select patient sub-populations for targeted therapy in the future. This review summarizes current data in this area and discusses their potential clinical relevance.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Human Pathology - Volume 46, Issue 6, June 2015, Pages 789–804
نویسندگان
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