کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4142415 | 1272372 | 2010 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Conferencia de Consenso sobre bronquiolitis aguda (V): prevención de la bronquiolitis aguda. Revisión de la evidencia cientÃfica
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
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چکیده انگلیسی
A review of the evidence on prevention of acute bronchiolitis is presented. Acute bronchiolitis prevention arises from three basic approaches: preventive treatment to reduce recurrent wheezing following an episode of acute bronchiolitis, preventive treatment to reduce the frequency and severity of RSV bronchiolitis in the population at risk (prematurity, bronchopulmonary dysplasia, congenital heart disease, etc.), and general preventive measures to reduce nosocomial infection with RSV. There is sufficient evidence on the lack of efficacy of inhaled corticosteroids, oral corticosteroids and montelukast. Intravenous RSV immunoglobulin has an unfavorable risk-benefit balance, particularly with the availability of monoclonal antibodies. Palivizumab is effective as preventive treatment of RSV infection in risk populations (high risk preterm infants and hemodynamically significant congenital heart disease), but not in the frequency and severity (ICU admission, need for mechanical ventilation and mortality) of the acute bronchiolitis. The benefits of palivizumab (less admissions) seem to be worth the adverse effects, but we do not know the cost-benefit ratio. The control and prevention measures of nosocomial transmission of RSV infection (isolation, hand washing, use of mask, gloves, cap and shoes) are based on indirect evidence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Anales de PediatrÃa - Volume 72, Issue 5, May 2010, Pages 353.e1-353.e26
Journal: Anales de PediatrÃa - Volume 72, Issue 5, May 2010, Pages 353.e1-353.e26
نویسندگان
J. González de Dios, C. Ochoa Sangrador, Grupo de Revisión, del Proyecto aBREVIADo (BRonquiolitis-Estudio de Variabilidad, Idoneidad y ADecuación) Grupo de Revisión, del Proyecto aBREVIADo (BRonquiolitis-Estudio de Variabilidad,