The effect of oxalic acid and glyoxal on the VO(acac)2-catalyzed cyclohexane oxidation with H2O2

A new protocol for the effective oxidation of cyclohexane in acetonitrile at 40 °C and atmospheric pressure into cyclohexanol, cyclohexanone and cyclohexyl hydroperoxide using hydrogen peroxide as the oxidant, vanadyl(IV)-acetylacetonate as the catalyst, oxalic acid and glyoxal as additives is presented with some reaction mechanism proposals.

Figure optionsDownload high-quality image (26 K)Download as PowerPoint slideResearch highlights▶ The benign process of cyclohexane oxidation by H2O2 was studied. ▶ Vanadyl(IV)-acetylacetonate, oxalic acid and glyoxal additives have been explored. ▶ The efficiency of such system in the enhancing of aimed products yield was revealed. ▶ The putative mechanism of the oxidation process was suggested.