Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosis

The study clearly demonstrated that pediatric patients with hydronephrosis and dysfunction had significantly higher uNGAL to creatinine concentrations as compared with controls.Table. Urine concentration of KIM-1/Cr, NGAL/Cr and L-FABP/Cr in patients and controls.ParametersGroup 1 (HN with obstruction)Group 2 (HN without obstruction)Control groupNGAL/Cr (ng/mg Cr)a1.8 (0-16)0.9 (0-21)0.5 (0-14)KIM-1/Cr (ng/mg Cr)169 (39-2809)215 (37-1351)159 (6-525)L-FABP/Cr (ng/mg Cr)1.2 (0-15)1.5 (0-11)0.8 (0-7)Cr: creatinine; HN: hydronephrosis, KIM-1: kidney injury molecule-1; L-FABP: liver fatty-acid-binding protein; NGAL: neutrophil gelatinase-associated lipocalin.ap<0.05 between group 1 and group 2; and between group 1 and controls.