کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4163593 1274310 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Prognostic value of serum creatinine levels in children with posterior urethral valves treated by primary valve ablation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Prognostic value of serum creatinine levels in children with posterior urethral valves treated by primary valve ablation
چکیده انگلیسی

PurposeWe evaluated the prognostic value of serum creatinine level at presentation and nadir creatinine during follow up for future renal function (RF) in children with posterior urethral valves (PUV).Materials and methodsBetween 1987 and 2004, 120 cases of PUV were treated initially at our hospital with valve ablation. Initial assessment included serum creatinine measurement, urine analysis and culture, renal ultrasonography and voiding cystourethrography. After valve ablation, renal ultrasound and serum creatinine measurement were repeated and thereafter during visits until the end of follow up.ResultsFollow up ranged from 2 to 12 years (mean = 4.4). Renal insufficiency (RI) developed at the end of follow up in 44 patients (36.5%). The mean initial and nadir serum creatinine in the RI group was higher than in the normal RF group (P < 0.05). With a cut-off value of 1 mg/dl for initial and nadir serum creatinine, the incidence of RI was significantly different (P < 0.05).ConclusionOur data confirm the high prognostic value of nadir serum creatinine after relief of valvular obstruction. Further, the serum creatinine level before valve ablation correlates significantly with long-term RF in children with PUV.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pediatric Urology - Volume 6, Issue 1, February 2010, Pages 11–14
نویسندگان
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