کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4170457 | 1607671 | 2007 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hyperinsulinisme congénital du nouveau-né : évolution après pancréatectomie subtotale
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
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چکیده انگلیسی
Congenital hyperinsulinism in newborns is a rare disease but it is a severe affection by its rebel hypoglycaemia that leads to important brain damage. We report the case of a full-term boy been born by caesarean for macrosomia with a born-weight of 4800 g. He presented from the first day of life severe and lasting hypoglycaemia in spite of a high glucose delivery rates (16 mg/kg per minute) and a treatment by diazoxide. The diagnosis of a congenital hyperinsulinism is then evoked and confirmed by several high insulinemia. Sandostatine was not accessible to this patient and a distal subtotal pancreatectomy was realized at 50 days of age. The anatomopathological examination of the pancreas does not find abnormalities. After a postoperative transient Diabetes mellitus, the glycaemia were normalized gradually. At five months of age, the glycemia was 4.8 mmol/L, the glycated haemoglobin (HbA1c) was 6.4% and the insulinemia was 1 μUI/mL. The transfontanelle ultrasonography and the electroencephalogram were normal. After two years of age, the child presents epilepsy mastered by the valproate of sodium and a severe psychomotor retardation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal de Pédiatrie et de Puériculture - Volume 20, Issue 8, December 2007, Pages 325-329
Journal: Journal de Pédiatrie et de Puériculture - Volume 20, Issue 8, December 2007, Pages 325-329
نویسندگان
H. Ben Hamouda, A. Bedoui, B. Mahjoub, H. Soua, A. Ayadi, Y. Belkhir, A. Zakhama, A. Nouri, A. Zbedi, M.-T. Sfar,