کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4172661 1275766 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Recent developments in the management of Duchenne muscular dystrophy
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Recent developments in the management of Duchenne muscular dystrophy
چکیده انگلیسی

Duchenne muscular dystrophy (DMD) is the most common paediatric muscle condition. Affected boys show first symptoms around the age of 2–5 years with progressive muscle weakness and wasting leading to severe disability and reduced life span due to cardiac and respiratory complications.Although no curative treatment is currently available for this severe and fatal condition, over the last years, advances in general care, corticosteroids and worldwide dissemination of standards of care especially in respiratory and cardiac care have changed the natural course of DMD. Careful and timely management of the disease, its complications and psychosocial aspects is mandatory. Such interventions have been shown to improve quality of life and prolong survival, so that most of patients now reach adulthood. Moreover, recent development of new therapeutic approaches and clinical trials require standardized treatment and management of these patients to evaluate the safety and efficacy of new compounds. The multi-systemic features of DMD require multidisciplinary team working, where paediatricians play an essential role in the management of patients, from diagnosis to planned transition into adult medical services.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Paediatrics and Child Health - Volume 21, Issue 11, November 2011, Pages 501–509
نویسندگان
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