The Use of Inactivated Influenza Vaccine in Children

The impact of influenza in the very young appears to be comparable to that in the elderly. Influenza vaccine strategy is changing to reflect that impact. Currently, the broader recommendations include vaccination with trivalent inactivated influenza vaccines (TIVs) for children aged 6 to 59 months. This article reviews TIV safety, immunogenicity, and efficacy in children, current vaccine recommendations, and vaccine administration and dosage.