کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4186297 | 1608178 | 2012 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: A systematic review of resting-state functional-MRI studies in major depression A systematic review of resting-state functional-MRI studies in major depression](/preview/png/4186297.png)
BackgroundTo evaluate the literature pertaining to the use of resting-state functional magnetic resonance imaging (fMRI) in Major Depression (MD).MethodsA search for papers published in English was conducted using MedLine, Embase, PsycINFO, OvidSP, and ScienceDirect with the following words: resting state, depression, MRI, affective, and default-mode.ResultsThe findings from 16 resting-state fMRI studies on MD are tabulated. Some common findings are discussed in further detail.ConclusionThe use of resting-state fMRI in MD research has yielded a number of significant findings that provide the basis for understanding the pathophysiology of depressive symptoms. Of particular note and deserving of further research are the roles of the cortico-limbic mood regulating circuit (MRC) and the interaction between task-positive and task-negative networks in MD. There is increasing interest in the use of resting-state fMRI in the study of psychiatric conditions, and continued improvement in technique and methodology will prove valuable in future research.
Journal: Journal of Affective Disorders - Volume 142, Issues 1–3, 15 December 2012, Pages 6–12