کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4187171 1608209 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Psychotic symptoms in patients with bipolar mania
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
پیش نمایش صفحه اول مقاله
Psychotic symptoms in patients with bipolar mania
چکیده انگلیسی

BackgroundPsychosis has been identified in as many as 68% of patients with bipolar mania. This analysis identified psychotic symptoms in these patients.MethodsData were from two placebo-controlled, 3-week studies in patients with an acute episode of bipolar mania. Symptoms were identified by the 30-item Positive and Negative Syndrome Scale (PANSS; item ratings, 1 = absent to 7 = extremely severe), the Young Mania Rating Scale, and the Global Assessment Scale.ResultsPsychotic features at study entry were diagnosed in 264 (51.3%) of the 515 patients. At baseline, these patients had significantly more severe scores on the PANSS, Young Mania Rating Scale, and Global Assessment Scale than patients without psychotic features. Patients with psychotic features had mean (± SD) scores of mild (3) or greater on six PANSS items: grandiosity (4.5 ± 1.4), delusions (4.4 ± 1.4), lack of judgment/insight (4.1 ± 1.5), excitement (3.9 ± 1.3), suspiciousness/persecution (3.1 ± 1.6), and hostility (3.1 ± 1.5). Grandiosity symptoms of delusional proportions (scores ≥ 4) were noted in 205 (78%) of patients with a diagnosis of psychotic features and in 113 (45%) patients without the diagnosis.LimitationsThe study was not specifically designed to assess patients with psychotic features and the PANSS was developed to evaluate symptoms of schizophrenia.ConclusionsThese findings support prior reports indicating high rates of psychosis in patients with bipolar mania and identify the most prominent symptoms in these patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Affective Disorders - Volume 111, Issues 2–3, December 2008, Pages 164–169
نویسندگان
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