کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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41950 | 45905 | 2010 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Synthesis of nitrile coordinated Lewis acids Al(OC(CF3)2R)3 and their application in catalytic epoxide ring-opening reactions Synthesis of nitrile coordinated Lewis acids Al(OC(CF3)2R)3 and their application in catalytic epoxide ring-opening reactions](/preview/png/41950.png)
Four nitrile ligated aluminum-based Lewis acids PhCNAl(OC(CF3)2PhCH3)3 (1), CH3CNAl(OC(CF3)2PhCH3)3 (2), PhCNAl(OC(CF3)2Ph)3 (3), CH3CNAl(OC(CF3)2Ph)3 (4) were synthesized and characterized by nuclear magnetic resonance and infrared spectroscopy, as well as X-ray crystallography. The ring-opening reactions of epoxides with aromatic/aliphatic amines were efficiently catalyzed by compounds 1–4 as catalysts in a concentration of 1 mol% under solvent-free conditions at room temperature, affording 2-amino alcohols in high yields (up to 99%) within 4 h. Compound 1, being the best catalyst, yields 70% product within 10 min.
Figure optionsDownload high-quality image (83 K)Download as PowerPoint slideResearch highlights▶ Aluminum-based Lewis acids catalyze epoxide ring opening with amines. ▶ The Al catalysts are more efficient than borane analogues. ▶ The shape and basicity of the amine influence the product yield.
Journal: Applied Catalysis A: General - Volume 384, Issues 1–2, 20 August 2010, Pages 171–176