کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4207691 1280358 2008 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Immune System in Critical Illness
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
The Immune System in Critical Illness
چکیده انگلیسی

The mammalian immune system comprises a complex network of physical and molecular elements that protect the individual from danger in the environment. An evolutionarily ancient innate immune system recognizes danger through pattern-recognition receptors that are encoded in the genome and mobilizes a rapid and potent but nonspecific response. This response is responsible for the clinical syndromes of sepsis and the multiple organ dysfunction syndrome. The adaptive immune system is highly selective in its targets and is endowed with memory but is slow in initial activation. Critical illness results in derangements of all components of the immune response, but the very complexity of the process has frustrated attempts to correct these derangements and to affect significantly the clinical course of sepsis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinics in Chest Medicine - Volume 29, Issue 4, December 2008, Pages 605–616
نویسندگان
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