کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4211498 1280643 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Epidemiology of acute lung injury and acute respiratory distress syndrome in The Netherlands: A survey
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
Epidemiology of acute lung injury and acute respiratory distress syndrome in The Netherlands: A survey
چکیده انگلیسی

SummaryBackgroundThe characteristics, incidence and risk factors for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) may depend on definitions and geography.MethodsA prospective, 3-day point-prevalence study was performed by a survey of all intensive care units (ICU) in the Netherlands (n=96). Thirty-six ICU's responded (37%), reporting on 266 patients, of whom 151 were mechanically ventilated. The questionnaire included criteria and potential risk factors for ALI/ARDS, according to the North American–European Consensus Conference (NAECC) or the lung injury score (LIS⩾2.5).ResultsAgreement between definitions was fair (κ 0.31–0.42, P=0.001). ALI/ARDS was characterized, regardless of definition, by radiographic densities, low oxygenation ratios, high inspiratory O2 and airway pressure requirements. Depending on definitions, ALI and ARDS accounted for about 12–33% and 7–9% of ICU admissions per year, respectively, constituting 21–58% (ALI) and 13–16% (ARDS) of all mechanically ventilated patients. The annual incidences of ALI and ARDS are 29.3 (95%CI 18.4–40.1) and 24.0 (95%CI 14.2–33.8) by NAECC, respectively, and are, respectively, 83.6 (95%CI 65.3–101.9) and 20.9 (95%CI 11.7–30.1) by LIS per 100,000. Risk factors for ALI/ARDS were aspiration, pneumonia, sepsis and chronic alcohol abuse (the latter only by NAECC).ConclusionThe effect of definitions of ALI/ARDS on mechanical ventilation in the Netherlands is small. Nevertheless, the incidence of ALI/ARDS may be higher than in other European countries but lower than in the USA, and the incidence of ALI by LIS may overestimate compared to that by NAECC. Aspiration, pneumonia, sepsis and chronic alcohol abuse are major risk factors, largely independent of definitions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Medicine - Volume 101, Issue 10, October 2007, Pages 2091–2098
نویسندگان
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