کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4212204 1280668 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
No further increase of incidence of asthma: Incidence, remission and relapse of adult asthma in Sweden
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
No further increase of incidence of asthma: Incidence, remission and relapse of adult asthma in Sweden
چکیده انگلیسی

SummaryBackgroundKnowledge about time trends of disease patterns in society is essential for planning and prioritizing health care resources. Longitudinal population-based studies on asthma are scarce but provide an opportunity to assess incidence, remission and relapse of asthma, and their determinants, which were the objectives of the present study.MethodsA postal questionnaire was sent on two occasions, 1996 and 2006, to a randomly selected sample of subjects aged 20–69 years in 1996. The response rates were 72% and 83%, respectively, and in total 4479 subjects participated in both surveys. The questionnaire included questions on asthma, respiratory symptoms and possible determinants. Logistic regression was used to assess determinants.ResultsCumulative incidence of asthma was 2.4% (men 1.9%; women 2.8%, p = 0.06). Family histories of asthma (OR 2.31, CI 95% 1.42–3.76), rhinitis (OR 2.25, CI 95% 1.43–3.53) and being an ex-smoker (OR 2.17, CI 95% 1.27–3.71) were determinants for incident asthma. The 10-year remission of asthma was 14.6% and inversely associated with rhinitis. Relapse was found in 38% of eligible subjects.ConclusionsThe current study with high participation rates concludes that the incidence of asthma among adults has been stable in Sweden for the past two decades. Remission was associated with mild disease at study start. Relapse in adults has rarely been reported previously and provide new insight in the course of asthma. Low remission and high relapse further support the view of asthma as a chronic disease; possibly representing fluctuations of the disease over time.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Medicine - Volume 102, Issue 12, December 2008, Pages 1730–1736
نویسندگان
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