Analysis of Vascular Complications After Renal Transplantation

PurposeDespite medical and surgical advances, vascular complications remain common after renal transplant, occurring among 3%–15% of patients. These complications may compromise graft function. This study sought to evaluate the frequency and management of vascular complications after renal transplant.Materials and MethodsWe retrospectively analyzed the 1843 transplantations performed at 2 centers by our team since November 1975. The 1349 male and 494 female patients had an overall mean age of 31.5 ± 11.2 years; (range, 3–66). Grafts were obtained from a living-related donor in 1406 (76.29%) or a deceased donor in the remaining 437 (23.71%). The mean donor age was 40.7 ± 13.7 years (range, 2–76). Of 1843 transplants, multiple vascular anastomoses were performed in 155 cases (8.4%), including 130 involving renal arteries and 25 renal veins.ResultsForty-seven vascular complications (2.55%) were observed in 43 procedures (2.33%), most frequently renal artery stenosis (n = 14). It was followed by allograft renal artery kinking (n = 7), renal vein kinking (n = 7), renal artery thrombosis (n = 5), renal vein laceration (n = 4), renal artery laceration (n = 3), renal vein thrombosis (n = 2), renal artery disruption (n = 2), renal and iliac vein obstructions owing to pressure from a lymphocele (n = 1), renal artery and vein obstruction owing to pressure from a hematoma (n = 1), or an arteriovenous fistula after percutaneous graft biopsy (n = 1). Fifteen of these 47 complications were treated by interventional radiologic procedures.ConclusionThe vascular complication rates in our patients were somewhat lower than those reported in the literature. A thorough understanding of how complications impair allograft function and survival is essential for adequate treatment. Interventional radiology is invaluable in the postoperative management of transplant-related complications.