کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4259570 | 1284573 | 2009 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Chronic Liver Allograft Dysfunction Chronic Liver Allograft Dysfunction](/preview/png/4259570.png)
Approximately 90% of liver transplant patients are alive after 1 year and 75% after 5 years with the majority leading full and near-normal lives. However, although early mortality rates after transplantation have fallen dramatically over the last 2 decades, the rates of late graft loss and patient death have remained constant. Thus, understanding of the causes of graft and patient failure is essential to improve long-term outcomes. In the early days after liver transplantation, ischemia and reperfusion injuries predominate, with acute cellular rejection relatively common in first 3 months. Thereafter, the causes of graft dysfunction are variable with disease recurrence as a major cause of graft loss. In this review, we discuss causes of graft dysfunction after 6 months.
Journal: Transplantation Proceedings - Volume 41, Issue 2, March 2009, Pages 773–776