Reconstitution of Human Lymphocytes Following Ex Vivo Expansion of Human Umbilical Cord Blood CD34+ Cells and Transplantation in Rag2−/− γc−/− Mice Model

These data suggested that the development of a diverse repopulation of human lymphocytes was possible in Rag2−/−γc−/− mice after transplantation of cultured UCB CD34+ HSCs with interleukin-3.