Assessment of Cyclosporine Pharmacokinetic Parameters to Facilitate Conversion From C0 to C2 Monitoring in Heart Transplant Recipients

In long-term heart transplant recipients, we could not identify a single pharmacokinetic parameter that could be used to develop an algorithm to convert from C0 to C2 monitoring; however, C2 may be better than C0 for identifying patients at risk of overexposure to CsA.