کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4264180 | 1284632 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The Evaluation of Apoptosis and Reactive Oxygen Species in Hematopoietic Cells Derived From Heparinized Cadaveric Organ Donors Stored Short-Term at 4°C
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
عمل جراحی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The Evaluation of Apoptosis and Reactive Oxygen Species in Hematopoietic Cells Derived From Heparinized Cadaveric Organ Donors Stored Short-Term at 4°C The Evaluation of Apoptosis and Reactive Oxygen Species in Hematopoietic Cells Derived From Heparinized Cadaveric Organ Donors Stored Short-Term at 4°C](/preview/png/4264180.png)
چکیده انگلیسی
Heparinized cadaveric organ donors are an important source of human organs and potentially of hematopoietic cells for transplantation purposes. The aim of this study was to evaluate the kinetics of programmed cell death in the hematopoietic cells harvested from these individuals and stored short-term at 4°C. We also attempted to assess hematopoietic cell oxidation by measuring reactive oxygen species (ROS) generated by the mitochondria of stored cells. We found that these bone marrow cells harvested and stored at 4°C for 7 days did not display a significant increase in programmed cell death. However, prolonged storage resulted in lower ROS production, indirectly giving evidence of activation of intracellular signaling proteins.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transplantation Proceedings - Volume 37, Issue 5, June 2005, Pages 2281-2284
Journal: Transplantation Proceedings - Volume 37, Issue 5, June 2005, Pages 2281-2284
نویسندگان
B. MachaliÅski, M. BaÅkiewicz-Masiuk, K. Pabisiak, K. Grymula, J. SieÅko, L. DomaÅski, M. Ostrowski, A. MachaliÅska,