کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4270073 1610877 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Peyronie's Disease Plaque Calcification—Prevalence, Time to Identification, and Development of a New Grading Classification
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی اورولوژی
پیش نمایش صفحه اول مقاله
Peyronie's Disease Plaque Calcification—Prevalence, Time to Identification, and Development of a New Grading Classification
چکیده انگلیسی

IntroductionPeyronie's disease (PD) is a connective tissue disorder of the penis in which a fibrous scar in the tunica albuginea can result in multiple penile deformities.AimThe study aims to investigate the prevalence and time to identification of plaque calcification (PC) in our PD patient population and whether stratification of calcification based on severity seen on ultrasound would serve as a predictor of treatment progression to surgery.MethodsA retrospective review of 1,041 men presenting with PD from 1993 to 2009 was performed. Eight hundred thirty‐four underwent penile duplex ultrasound.Main Outcome MeasuresPC was graded as: grade 1 (<0.3 cm), grade 2 (>0.3 cm, <1.5 cm), grade 3 (>1.5 cm; or ≥2 plaques >1.0 cm). A matched control group with noncalcified plaques (n = 236) was selected for comparison.ResultsTwo hundred eighty‐four men (34%) were found to have PC noted on ultrasound, and 98 had fully documented dimensions of the PC. Forty‐one percent were found to have grade 1, 28% grade 2, and 32% grade 3. When analyzed by grade and progression to surgery, 23% of grade 1, 32% of grade 2, and 55% of grade 3 patients had surgery. Those with grade 3 PC were more likely to undergo surgical intervention for PD (OR 2.28 95% CI 1.07–4.86) and more likely to undergo a grafting procedure than control patients (P < 0.0001).ConclusionsMen with PC are not more likely to undergo surgery than those without PC (OR 0.95, 95% CI 0.58–1.57). PC is not uncommon, as it was found in 34% of our cohort. PC does not appear to be an indication of mature or stable disease, as it was identified by ultrasound in 37% of patients less than 12 months after onset of symptoms. Men with grade 3 PC have an increased likelihood of progression to surgical intervention and a higher likelihood of undergoing a grafting procedure. Levine L, Rybak J, Corder C, and Farrel MR. Peyronie's disease plaque calcification—prevalence, time to identification, and development of a new grading classification. J Sex Med 2013;10:3121–3128.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Sexual Medicine - Volume 10, Issue 12, December 2013, Pages 3121–3128
نویسندگان
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