The Antidepressants Fluoxetine and Bupropion Differentially Affect Proceptive Behavior in the Naturally Cycling Female Rat

The motivational components of female sexual behavior are more sensitive than the receptive components to the inhibitory actions of fluoxetine. Bupropion selectively stimulated hopping/darting, while yohimbine lacked an action on female sexual behavior. Ventura-Aquino E and Fernández-Guasti A. The antidepressants fluoxetine and bupropion differentially affect proceptive behavior in the naturally cycling female rat. J Sex Med 2013;10:2679-2687.