Anandamide Transforms Noncopulating Rats into Sexually Active Animals

The endocannabinoid anandamide transforms previously NC rats into sexually active animals, capable of showing sexual behavior in a long-lasting manner. Only half of the NC population responds to anandamide injection, suggesting that different mechanisms underlie the sexual inhibition of NC rats. The endocannabinoid system seems to play a role in the regulation of male rat sexual behavior expression. Canseco-Alba A and Rodríguez-Manzo G. Anandamide transforms noncopulating rats into sexually active animals. J Sex Med 2013;10:686-693.