Flow‐Evoked Vasodilation Is Blunted in Penile Arteries from Zucker Diabetic Fatty Rats

The present findings show that flow evokes endothelium‐dependent EDHF‐type vasodilation involving BKCa channels in penile arteries. Flow‐evoked vasodilation is reduced and only of EDHF‐type in penile arteries from type 2 diabetic rats suggesting modulation of this pathway may restore endothelial function and preserve erection in diabetes. Schjørring O, Kun A, Flyvbjerg A, Kirkeby HJ, Jensen JB, and Simonsen U. Flow‐evoked vasodilation is blunted in penile arteries from Zucker diabetic fatty rats. J Sex Med 2012;9:1806-1817.