Oral Agents for the Treatment of Premature Ejaculation: Review of Efficacy and Safety in the Context of the Recent International Society for Sexual Medicine Criteria for Lifelong Premature Ejaculation

This systematic review of well‐controlled clinical trials in PE has demonstrated that while many oral agents, particularly SSRIs, tramadol, and dapoxetine, have proven effective and safe for the treatment of men with PE, few have been evaluated for their effects on the specific elements of the ISSM criteria. McMahon CG and Porst H. Oral agents for the treatment of premature ejaculation: Review of efficacy and safety in the context of the recent international society for sexual medicine criteria for lifelong premature ejaculation. J Sex Med 2011;8:2707-2725.